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This is significant, considering that data from Blue Cross Blue Shield found that over 63% of GLP-1 patients from 2014 to 2023 were in this age group

This finding was so striking that Wegovy is now indicated for overweight and obese patients with heart disease

In the HARMONY-2 (efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide) clinical study, patients were randomized to receive either once-weekly albiglutide (30 mg, titrated up to 50 mg if required for glycemic control) or 10 units of insulin glargine once daily

In a statement, Regeneron revealed that the combination was unable to show a statistically significant improvement in median progression-free survival (PFS) compared to Keytruda, although, there was a numerical extension of 5.1 months with the highest dose 11.5 months versus 6.4 months which was not far off the threshold for significance

The work was funded by Novo Nordisk A/S, Denmark