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GLP-1 drugs are quickly becoming some of the most ubiquitous in the U.S., and they have drawn interest for their potential use in treating alcohol use disorder.

Their pleiotropic benefits arise from intricate signalling cascades that regulate appetite, insulin secretion, and energy homeostasis across multiple tissues.

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An effective treatment might require either utilization of multiple drugs which target the individual pathological processes which underlie the neurodegenerative disease or the use of a single agent which could influence multiple pathological processes

FDA approval is anticipated in 2026, through the FDA's national priority voucher program, positioning Lilly to compete aggressively in the oral segment

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