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Patients with T2DM have twice the risk of CVD mortality compared with age-matched subjects without T2DM, approximately 10% increased risk of cancer, and poorer survival rates of cancer [4,5,6]

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Some patients report feeling less bloated or puffy within days of starting treatment, while others notice improved ring or shoe fit as water shifts out of subcutaneous (under-skin) tissue

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Despite being intended to treat depression, sertraline has long been used as an off-label treatment for PE.10 Sertraline is a daily medication
