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Consistent with our findings in HepG2 cells, the in vivo studies also showed that HFD feeding markedly inhibited the acetylation of histone 3, and this effect was reversed by NaB treatment (Fig
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Currently, there is no known antidote to reverse tirzepatide overdose, but supportive care is indicated for control of symptoms [11]
That result is encouraging, but it was observational, so it shows an association rather than proof of prevention
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