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If side effects remain disruptive despite thoughtful dose adjustments, nutrition changes, and real follow-up, it may be time to consider a different strategy

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Two studies reported a significant reduction in lower limb amputations (LLA) and diabetic foot ulcers, while one study found no significant difference in LLA compared to other diabetic therapies

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Is muscle loss a concern with GLP1 therapy

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Restoring this balance requires more than just probiotics

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The STEP 1 clinical trial demonstrated average weight loss of approximately 15% of initial body weight when combined with lifestyle modifications

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This lifts the subcutaneous layer away from underlying muscle

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