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GLP-1s anti-inflammatory effects GLP-1 receptor agonists significantly reduce inflammation by modulating immune cell activity and suppressing the release of pro-inflammatory cytokines, such as TNF- , IL-6, and IL-1 (99101)
10 , 17 If the dose is fixed at 2.4 mg but the dosing interval is increased to 14 days (q2wk), the model predicts a steadystate body weight reduction of 12%

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Annu Rev Med 74:125139
Efficacy and safety of onceweekly semaglutide versus exenatide ER in subjects with type 2 diabetes (SUSTAIN 3): a 56week, openlabel randomized clinical trial

If you were a betting person, youd probably bet that wed end up with nothing. Its very rare, frankly, that something goes this way and that frequently its a combination of luck, some intelligence, some foresight into doing the right experiments, Raufman said
