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doi: 10.3389/fnins.2025.1534061

Have a history of diabetic retinopathy

Contact your healthcare provider if you experience unusual symptoms that don't resolve within the expected 4 to 5 week window

announced the decision to discontinue the development of danuglipron (PF-06882961), an oral glucagon-like peptide-1 (GLP-1) receptor agonist, which was being investigated for chronic weight management

Adjustments to this schedule may be made by healthcare providers based on how well the individual tolerates the medication

Ubiquitylation is known to be intricately regulated and often exhibits crosstalk with other PTM processes, and considering the established regulatory crosstalk between protein glycosylation and ubiquitylation that governs protein stability, [ 56 ] we hypothesize that such mechanisms could be at play here