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1 These agents also delay gastric emptying and reduce appetite via central mechanisms, thereby contributing to their metabolic effects

While a calorie deficit is needed for weight loss, cutting calories and protein too much can lead to muscle loss and fatigue

not for use during pregnancy or with a personal or family history of medullary thyroid cancer

This makes it a valuable tool for individuals looking to lose weight and improve liver health

So this is the first dual GLP-1 glucagon agonist to publish phase three results

Results The 43 included studies were published between 2013 and 2025 and originated from diverse regions including Belgium, France, China, and the United States