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Description
These mediators can induce the production of MMPs and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) by chondrocytes and further degradation of the cartilage, contributing to a cycle of inflammation and disease 7,10
This creates a system where a simple yes or no is impossible without a full clinical review

Execution is what changes outcomes

Consult a pharmacist for specific interaction advice
Zepbound (tirzepatide) injection: prescribing information
adjusted HR 1.18)
