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Obesity was often overlooked at many pharmaceutical companies, and it took investing billions of dollars in the face of significant criticism to get us here
Shortening the interval raises the steady-state concentration too fast, amplifying side effects without any proven safety or efficacy benefit
Front Endocrinol (Lausanne) 2018;9:672
doi: 10.1021/jf072589s
The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes
The primary endpoint was the percentage of patients achieving an A1C of less than 7%
