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Biochemistry 57 , 41484154 (2018)

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Preclinical and clinical studies have shown that GLP-1s reduce alcohol intake, blunt the pleasurable effects of opioids and stimulants, and might reduce cravings across multiple substance classes

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Blood 97 , 27022707 (2001)

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Many people begin in their late twenties or early thirties when they notice early expression lines or want to take a preventative approach

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The Ideal GLP-1 Snack Contains: 15-20g protein (enough to support muscle, not so much it's too filling) 150-200 calories (substantial but not meal-sized) Low to moderate fat (5-10g maxhigh fat worsens GLP-1 nausea) Minimal added sugar (under 10gsugar can trigger blood sugar swings) Small volume (your stomach empties slowly on GLP-1s) Easy to digest (avoid gas-producing or heavy foods) Timing Your Snacks Most people do well with this pattern: Mid-morning (10-11 AM): 3-4 hours after breakfast, before lunch Mid-afternoon (3-4 PM): 3-4 hours after lunch, before dinner This creates 5-6 eating occasions spread throughout the daysmall, frequent, protein-focused

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Nonetheless, the ability of L-cells to secrete GLP-1 in direct response to luminal nutrients certainly plays an additional role, and may be the main mechanism of GLP-1 secretion

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