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References Saxenda FDA Approval History

It may also inhibit the neurons in the ARC that contain POMC-derivative a-MSH that mediate the anorexigenic effect in the ventromedial hypothalamus (36)

A more recent study found that liraglutide activates GLP-1R-expressing neurons in the DMH, which then inhibit NPY/AgRP neurons in the ARH, thereby suppressing food intake [8]

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