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Laboratory studies demonstrate that GLP-1 receptor agonists suppress macrophage secretion of multiple inflammatory cytokines including IFN-gamma, IL-17, IL-2, TNF-beta, IL-6, and IL-1beta

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GLP-1 RAs promote weight loss primarily by reducing appetite and improving metabolic regulation

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Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4

From a recent Reuters article , ResMed CEO Michael Farrell said he thought weight-loss drugs wouldnt have a major impact on the companys future salesEven so, ResMeds stock has since lost about a third of its value