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Endocrinology, 152, 31033112

PlexusDx's Precision Peptide Genetic Test identifies your peptide-pathway variants across 14 pathways and 49 peptides, helping predict your likely response before starting treatment

[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Mahase E

"Oral semaglutide 25 mg builds on the proven efficacy and established safety and tolerability profile of semaglutide and represents a significant advancement in obesity treatment," said Dr
However, some patients reported reduced appetite and gastrointestinal discomfort, which may impact tolerability

The ensuing negative feedback loop may involve not only EECs but also Paneth cells and intestinal intraepithelial lymphocytes, as these cells have been reported to express the receptor for GLP-1 (namely GLP-1R), and loss of GLP-1R increases the severity of DSS-induced intestinal injury8, 9
