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For example, if the blood flow is reduced to 200 mL/min (to make the math easy), a 15 second flush will provide a 50 ml saline bolus

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They also suppress glucagon release, a hormone that raises blood glucose

The main findings so far are dose-dependent weight loss in phase 2 studies, frequent gastrointestinal side effects, and ongoing questions about long-term safety, eligibility, and approval

Sip this one slowly over 20-30 minutes

Conclusion: The perioperative management of patients taking incretinbased therapies (GLP1 and GIP receptor agonists) and SGLT2 inhibitors is evolving as these drugs gain widespread use for diabetes, obesity, and cardiorenal protection