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Available strengths range from 0.25 mg up to 2.5 mg weekly, with total peptide content adjusted accordingly (weekly dose 4)

These effects were observed with central, but not peripheral, administration of the agonist and antagonist, suggesting receptor expression on the luminal, CSF-facing side of the choroid plexus, which aligned with GLP-1R-mediated modulation of luminally-expressed transporters in excised choroid plexus

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