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Caspase inhibition prevents cardiac dysfunction and heart apoptosis in a rat model of sepsis

In the SURPASS-2 trial, patients on tirzepatide 15mg lost 13.1% body weight compared to 6.7% with semaglutidenearly double the loss

In this trial, treatment with Pfizers drug led to a 92% reduction in bleeding in patients lacking inhibitors to factor VIII or factor IX

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The FDA has issued communications addressing risks associated with some compounded GLP-1 products, and in early 2026, FDA issued warning letters to certain telehealth companies regarding marketing claims about compounded GLP-1 products
