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and inter alia, further down-regulates insulin function and thereby exacerbates Metabolic Syndrome!

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Which Is Better for Weight LossSemaglutide or Tirzepatide

The study (NCT03131687) was approved by the relevant ethics committees and conducted in accordance with the principles of the Declaration of Helsinki, Council of International Organizations of Medical Sciences International Ethical Guidelines, and Good Clinical Practice guidelines

2 Materials and methods 2.1 Trial design We conducted an observational study including women with PCOS and obesity, followed up at the outpatient clinics of the Department of Endocrinology, Diabetes, and Metabolic Diseases at the University Medical Centre Ljubljana, who continued treatment with metformin 2 years after discontinuation of short-term intervention with semaglutide as an add on to metformin therapy
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