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Over 16 weeks, the median body weight dropped from 223 lbs (101 kg) to 203 lbs (92 kg)
The positive charge at Lys-288 of the glucagon-like peptide-1 (GLP-1) receptor is important for binding the N-terminus of peptide agonists
2022;14:e32610
Pre-clinical findings and early retrospective data are encouraging
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