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Along these lines, increased duodenal contractility by the ENS is characteristic of T2D and likely contributes to metabolic dysfunction

Monotherapy with the once-weekly GLP-1 analogue dulaglutide for 12 weeks in patients with type 2 diabetes: dose-dependent effects on glycaemic control in a randomized, double-blind, placebo-controlled study

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Some people also feel less hungry and eat less

In other CVOTs most patients received target dose (maximal tolerated dose) and no analysis was done regarding dose-dependent effects