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July 2024 Study Links Active Ingredient in Some GLP-1 Drugs to Vision Loss A new study published in the Journal of the American Medical Associations Ophthalmology linked semaglutide drugs to a type of eye strokes called nonarteritic anterior ischemic optic neuropathy (NAION)

Your healthcare team may recommend temporarily reducing your dose, extending the time between dose increases, or implementing additional supportive measures

only 12.4% total body weight loss for semaglutide

This is negligible and well within safe limits

Additionally, there is a long-term risk of gallstone formation (cholelithiasis), which may be brought on by modifications in the drug's effects on bile composition and gallbladder motility