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Insulin Dose Reduction at GLP-1 RA Initiation In the SUSTAIN-5 trial (N=397), patients on semaglutide 1 mg plus basal insulin experienced a symptomatic hypoglycemia rate of 11.3%, versus 1.1% in the semaglutide-plus-metformin-only arm [6]

Moreover, the study groups considerably differ in size (52600 vs

Subsequently, the BPI product received final FDA approval. The company also noted that neither Belcher nor BPI have ever had Warning Letters issued to them from the FDA

2 Researchers analyzed data from 47,199 patients with cardiovascular disease who received semaglutide for up to two years

doi:10.1016/S0140-6736(17)30933-9 66