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It has been shown to respond to a range of physiological stimuli and is believed to be a good model cell line of GLP-1 secretion

[DOI] [PMC free article] [PubMed] [Google Scholar] [40].Kyriakidou A, Kyriazou AV, Koufakis T, et al

Thanks for this great review showing the need to move the paradigm away from just small solute clearance as a measure of PD prescribing

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HbA1c levels typically rise within months of stopping GLP-1 therapy, often returning towards pre-treatment values, as the underlying insulin resistance and beta-cell dysfunction remain
