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These conditions can make weight loss more difficult and increase the need for medical support

Zuber V, Grinberg NF, Gill D, et al

Preclinical studies has demonstrated that liraglutide enhances NK cell-mediated anti-tumor immune responses by inhibiting the IL-6/STAT3 signaling pathway in hepatocellular carcinoma cells and enhances NK cell functionality in obese patients [91]

The switch may cause transient weight fluctuation (1 to 3 pounds) during washout or titration, but this does not erase prior progress

Treat patients with noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH), previously called nonalcoholic steatohepatitis (NASH), with moderate to advanced liver fibrosis (stages F2 to F3)