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Tirzepatide, an injectable medication initially approved for type 2 diabetes, has emerged as a promising option for weight loss in non-diabetics

Retatrutide is a synthetic triple receptor agonist peptide targeting GLP-1, GIP, and glucagon receptors

Finally, we discuss the effective lifestyle and pharmacological interventions for IR and emphasize the necessity of incorporating IR management into the prevention, stratified diagnosis and treatment of HCC.

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