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Obesity phenotypes and their paradoxical association with cardiovascular diseases

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It has been reported that GLP-1 can improve energy efficiency by increasing glucose assimilation in the heart, which promote cardiac performance [60, 61]

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Research continues into additional applications

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A 2025 body-composition substudy added detail on fat-mass versus lean-mass changes within the T2D Phase 2 cohort fat mass accounted for the majority of total weight reduction (PMID 40609566)

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