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The drugs of interest included FDA-approved GLP-1RAs [26]: semaglutide, liraglutide, dulaglutide, exenatide, lixisenatide, and albiglutide
Your genes can impact how you respond to a GLP-1 In a study published in Genome Medicine , researchers found that about 10 percent of people carry certain variants of whats known as the PAM gene, and those individuals had a weaker blood sugar response to GLP-1based drugs compared to non-carriers
No significant sex- or weight-based risks were noted for liraglutide or tirzepatide
Liraglutide-induced acute kidney injury
Synergistic Metabolic Effects (Combined Therapy) Additive Clinical Benefits Combining GLP-1 RA and SGLT2i targets multiple metabolic pathways simultaneously
doi: 10.1126/scitranslmed.aar7047 101 FDA U
