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Clinical trials showed weight reductions between 1020%, leading to FDA approvals and widespread enthusiasm

The next generation of GLP-1s, which is expected to be launched next year, may demonstrate amplified effects that could include improved neuroprotection, Thiara says, but its impact would need to be validated through rigorous clinical trials, she stated

Nonetheless, patients with severe liver disease should be monitored more closely when initiating or discontinuing treatment

(2007) Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP

CRediT authorship contribution statement Aravinthan Vignarajah: Writing original draft, Methodology, Formal analysis, Data curation, Conceptualization

[DOI] [PubMed] [Google Scholar] 83.Durak A, Turan B