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Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin

Carefully selecting WRCs as follow-on/lead indications to gain reimbursement across markets where weight loss is unlikely to get covered, developing well thought out go-to-market strategy including direct-to-consumer and digital health models, and ensuring there is adequate manufacturing capacity to meet demand are also critical to success

Glucagon-like peptide-1 receptor agonists or GLP-1 RA definition includes a class of medications that act in a similar manner to the GLP-1 hormone

Of the two main incretin hormones released with food ingestion, the actions of glucagon-like peptide-1 (GLP-1) have been exploited for therapeutic benefit

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EXAMPLES OF SWITCHING TO OW SEMAGLUTIDE Four case studies are provided in Figure 3, based on the authors clinical experience, to illustrate the considerations when switching from one GLP1RA to another, using OW semaglutide as an example