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doi: 10.1161/CIRCULATIONAHA.118.036418 42 MarsoS

In 2022, WHO recorded that 43% of adults (18 years and above) globally were overweight and 16% were living with obesity

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5052 There is also accumulating pre-clinical evidence that GLP-1 and GLP-1RAs may modulate several dysregulated inflammatory pathways and immune cell lineages relevant to IBD, although some findings derive from studies in non-intestinal epithelial or immune cell lineages