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science glp 1 Science's 2023 Breakthrough of the Year: Weight loss drugs with a real shot at fighting obesity | The GLP -1 Revolution Goes
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doi: 10.1016/j.jad.2018.04.042
To our knowledge, at the time of writing there are no trials exploring weight loss in people without T2D

P.van OnzenoortH

During the titration period and early weeks of therapy, a blander, lower-fat diet reduces GI disturbance

Overall, these results indicate GLP-1RAs can influence a number of proteinopathies across disease models, although more understanding is required to determine when in the course of disease proteostasis can be modulated to bring about reduced neuronal loss and clinical benefit
Molecules 27 (19), 6280
