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The discovery of leptin almost 30 years ago as an adipocyte-derived hormone has attracted attention toward developing antiobesity therapies because of leptins potent effects in reducing food intake and enhancing energy expenditure (59)
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1017 In the LEADER trial, liraglutide resulted in a 22% reduction in adverse renal outcomes (HR 0.78
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A C18 fatty-diacid moiety via a linker enables albumin binding in assay media
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