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When this happens, compounding pharmacies (such as those that work with telehealth companies) are able to make formulations of a drug that is not readily available

However, if your weight loss driver involves metabolic slowdown, fat storage (influenced by FTO variants), or carbohydrate cravings rather than appetite, tirzepatide alone may produce underwhelming results

It is posited that these variations in expression and function contribute to the unique clinical attributes seen in clinical trials

Good sources include lean poultry, fish, eggs, Greek yogurt, cottage cheese, legumes, and tofu

1 The most recent clinical trial, SURMOUNT-1, reports that the average weight loss among over 2500 trial participants was 16% at 72 weeks

Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes-2022