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J Clin Endocrinol Metab 2014;99(3):800807

From Adjustment Phase to Long-Term Effects When starting GLP1 therapy, many clients first notice slowed gastric emptyingcausing nausea, bloating, and constipation

These results held across different body weight categories and age ranges, indicating consistent efficacy in diverse populations

Endocannabinoids in pain modulation

Patients who are desperate to start or continue their treatment might not follow the recommended step-up approach, increasing their risk of severe side effects

Common side effects include: Nausea Vomiting Diarrhea or constipation Reduced appetite Less common considerations: Injection-site reactions Temporary digestive discomfort Rare skin-related reactions Any worsening of skin symptoms should be reported to a healthcare provider promptly