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Crabtree TSJ, Adamson K, Reid H (2022) Injectable semaglutide and reductions in HbA1c and weight in the real world in people switched from alternative glucagon-like peptide-1 receptor agonists

The study found a substantially increased risk of NAION among individuals prescribed semaglutide relative to those prescribed other medications to treat type 2 diabetes and obesity or overweight. But this month, another cohort study with 135,000 participants looked at NAION in people with type 2 diabetes, obesity, or both

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The mechanism underlying constipation relates to the medication's effect on gastrointestinal motility
Wegovy is not recommended for individuals who: Have a personal or family history of medullary thyroid cancer (MTC) or MEN2 Are pregnant or planning to become pregnant Are breastfeeding Have had a serious allergic reaction to semaglutide or any of its ingredients 8

This approach aligns with emerging trends in nanomedicine, emphasizing multifunctional, biocompatible, and environmentally sustainable nanocarriers for complex neurodegenerative diseases
