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GLP-1, a hormone secreted by the intestines, lowers blood glucose and promotes weight loss through multiple mechanisms: it enhances insulin secretion in a glucose concentration-dependent manner, suppresses glucagon release, delays gastric emptying, and reduces food intake via central appetite suppression
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The FDA has granted accelerated approval of Wegovy (semaglutide) for adults with moderate to advanced metabolic dysfunction-associated steatohepatitis (MASH)
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