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Learn how an unlikely discovery in a venomous lizard led to one of todays most influential drugs and why future breakthroughs still depend on the freedom to explore.

Clinical studies after marketing have shown that the use of glucagon-like peptide-1 receptor agonist(GLP-1RA) may lead to acute kidney injury(AKI)

#VAResearchNewsBrief: Researchers from @OVAHCS and the @UF reported Veterans with non-alcoholic liver disease who were prescribed GLP1-RA had less liver disease progression and were less likely to die of heart attacks

Functional analyses demonstrated that i ) DIV-1 is required for the robust proliferation typical of the germline, ii ) loss of DIV-1 enhances and suppresses specific phenotypes that are associated with reduced and elevated GLP-1/Notch activity in germline and somatic tissues, and iii ) DIV-1 works together with FBF/PUF proteins, downstream regulators of GLP-1/Notch signaling, to promote germline stem cell (GSC) maintenance and germline proliferation

And they don't depend on each other to work.