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Common AEs were nausea (23%), vomiting (6%), diarrhea (6%), constipation (10%), headache (6%), fatigue (8%), abdominal pain (2%), and abdominal bloating (2%)

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**Analysis of single-cell RNA sequencing data from Crohn's disease (CD) patients:** Publicly available single-cell RNA sequencing data from mucosal biopsies of CD patients was used to confirm findings from murine models

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