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Researchers compared nearly 53,000 Wegovy patients to the same number of closely matched users of other weight-loss drugs

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Semaglutide works by mimicking the action of GLP-1, a naturally occurring incretin hormone that enhances insulin secretion, suppresses glucagon release, and slows gastric emptying

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semaglutide in France at the pre-specified timepoints for cohort 1, for cohort 2, and overall (Supplementary Material, Tables S5a to S5d)

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Ultimately, semaglutide works for weight loss because of the higher levels of the mimicked GLP-1 hormone in the body, which kicks natural responses into a higher gear

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GLP-1 Receptor Agonists and Metabolic Adaptation

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5C/D, Supplementary Figs

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