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(56) reported that the UCP-2 mRNA expression in intra-abdominal adipose tissue was significantly lower in obese subjects than that in lean ones

As research has progressed, it has been revealed that vagal sensory neurons distributed in the intestinal and hepatic portal regions play a crucial role in sensing circulating GLP-1 and mediating its physiological actions

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Nutrient stimulation causes an intracellular increase in both cAMP and Ca 2+ which then mediates GLP-1 secretion (114)

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For migraine-prone individuals, microdosing has a specific appeal