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As a licensed physician with over a decade of expertise in functional diagnostics, systems-based education, and clinician mentorship, Dr

Here are the most frequently reported: Nausea: Some people feel queasy or experience stomach discomfort, especially if the medication is taken without food

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Studies have shown that activation of the GLP1 receptor downregulates the expression of NADPH oxidase NOX3 and mitochondrial superoxide dismutase SOD2, thereby reducing ROS levels, blocking the oxidative stress-induced upregulation of Beclin1 expression and increased LC3-II/I ratio, and delaying autophagosome formation [57]

doi: 10.1136/bmj.l4898 60 BethelMAPatelRAMerrillPLokhnyginaYBuseJBMentzRJet al