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Description
Increased intestinal permeability ("leaky gut") allows bacterial lipopolysaccharides (LPS) to enter the bloodstream, triggering systemic inflammation that impairs insulin signaling

Diarrhea and Constipation Both diarrhea and constipation are frequent side effects of GLP-1 medications

doi: 10.1210/endo.136.11.7588224
Instead of several months, treatment may extend to a year or more

Neuron 51, 801810

[DOI] [PubMed] [Google Scholar] Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fo BA, et al
