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This glucose-dependent insulinotropic effect is particularly favorable for diabetes treatment because it avoids the risks of hypoglycemia, a common side effect of some anti-diabetes drugs, including insulin [9]

While the two medications belong to the same drug class, they have different mechanisms of action

For example, while GLP-1 RAs carry a low intrinsic risk of hypoglycemia, the addition of a GLP-1 RA to background sulfonylurea or insulin therapy can increase the risk for treatment-emergent hypoglycemia

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Zepbound is part of a medication class called dual glucose-dependent insulinotropic polypeptide (GIP)/glucagon-like peptide-1 (GLP-1) receptor agonists

The medication is primarily used for type II diabetes management