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GLP-1 receptor agonists are being studied for IBS symptom relief, with emerging research showing potential benefits for gut motility and visceral sensitivity

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Nearly 2.2 million patients were prescribed a GLP-1 RA between January 2019 and December 2025, according to the study.

Purpose of Review This review summarizes the current understanding of the physiologic influence of GLP-1 RAs on gastrointestinal motility, highlights key clinical implications of these effects, and defines areas for future investigation

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