tirzepatide and ozempic more effective in blood sugar control body weight loss than semaglutide Mounjaro vs. Ozempic: What's the
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It is not always a one-to-one transition in terms of potency or expected weight loss. And like the injectable versions, the medication alone is not the whole plan

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Another possible explanation for the limited body weight decrease is an increase in glucagon effects, with promotion of renal and hepatic gluconeogenesis and a consequent increase in endogenous glucose production

A 2024 analysis in The Lancet Diabetes & Endocrinology found that of the total weight lost on GLP-1 receptor agonists over 36-72 weeks, 25-39% represented lost muscle mass (rather than fat loss) [4]
This puts patients at increased risk for complications such as hematomas or supratherapeutic INR
