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[DOI] [PubMed] [Google Scholar] 83.Marso S.P., Bain S.C., Consoli A., Eliaschewitz F.G., Jdar E., Leiter L.A., Lingvay I., Rosenstock J., Seufert J., Warren M.L., et al
Current Clinical Pharmacology
Recurrent nocturnal hypoxic episodes promote oxidative stress and inflammatory activation, characterized by elevated TNF- , IL-6, and C-reactive protein levels (35)
Effective patient counseling on timing can greatly improve therapeutic outcomes and prevent unnecessary dose escalation
Behavioral anchors matter equally
Whether or not initial up-titration has to be recommended for a given compound/preparation depends on these agents pharmacokinetic properties
