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This review brings together a detailed overview of the mechanisms, clinical evidence and upcoming uses of GLP-1 agonists in CVDs, focusing on their use in the prevention, treatment, and future treatment possibilities, including dual agonists

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The weight loss that occurs during dieting, surgery or with GLP-1 receptor agonism is driven by significant reductions in both lean and fat mass [9]

Mireia Montaner, GLP-1 researcher at the University of Cambridge, said although there is still motivation to enhance GLP-1-based weight loss drugs, the idea of combining strategies, or even designing completely new ones, has equal or even greater interest. While these mixed approaches offer more feasible options for near-term improvements to obesity treatments than drug targeting to specific brain areas, scientists remain optimistic

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Thats especially relevant since constipation is one of the most commonly reported GLP-1 side effects