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A 2023 study in the journal Diabetes, Obesity and Metabolism examined hormonal changes in men on semaglutide and found improvements in testosterone levels that were partially, but not entirely, explained by weight loss alone
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Abstract The glucagon-like peptide-1 receptor agonist (GLP-1RA) semaglutide is the most recently approved agent of this drug class, and the only GLP-1RA currently available as both subcutaneous and oral formulation
It can also be used to lower the risk of heart attack, stroke, and cardiovascular death in adults with both Type 2 diabetes and heart disease
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However, it can be helpful to increase that activity to 250 minutes per week to maintain weight loss
