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The number of circulating CAR-T cells gradually decreased after treatment, declining to 20% of initial levels after four months, indicating that repeated administration may be required to sustain therapeutic efficacy

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Methods Plasmid construction The Exe4 gene was codon-optimized using the GeneSmart codon optimization tool ( based on the amino acid sequence in existing publication (Supplementary Table 1)

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They also slow gastric emptying so you stay full longer, reducing appetite and increasing satiety

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These anatomical factors exist regardless of medication use

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