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Mu Y, Gage FH

Of note, even before the introduction of the newer classes of medications, multifactorial, target-driven therapies addressing glycaemic, blood pressure and lipid control that incorporated reninangiotensin system blockade, the use of statins and attention to lifestyle factors significantly reduced the progression to end-stage kidney disease by about 50% in people with type 2 diabetes, hypertension and microalbuminuria

Sleep deprivation affects the balance of hunger-regulating hormones, leading to increased appetite and cravings for calorie-dense foods

The EMA reported that semaglutide users faced more than double the risk of developing NAION compared to patients on other diabetes medications and recommended updating drug labels to reflect this risk

In: Sensory and metabolic control of energy balance , 1st ed

A meta-analysis of 55 randomized controlled trials (comprising 33,350 participants) showed no statistically significant increase in the risk of pancreatitis with GLP-1 agonists compared with controls (OR: 1.05, 95% CI: 0.37-2.94)